The biodegradation of methoxyflurane begins immediately after the onset of exposure.
2.
Older, less popular, volatile anaesthetics, include halothane, enflurane, and methoxyflurane.
3.
Similar to its induction pharmacokinetics, methoxyflurane has very slow and somewhat unpredictable emergence characteristics.
4.
The longest time to emergence was 285 minutes, after 165 minutes of methoxyflurane administration.
5.
Trials of methoxyflurane as an analgesic in emergency medicine are going on in the UK.
6.
Due to the risk of organ ( especially renal ) toxicity, methoxyflurane is enzyme-inducing drugs.
7.
Reports of severe and even fatal hepatotoxicity related to the use of methoxyflurane began to appear in 1966.
8.
Furthermore, the concurrent use of tetracyclines and methoxyflurane has been reported to result in fatal renal toxicity.
9.
Fluorine-substituted ethers are volatile anesthetics, including the commercial products methoxyflurane, enflurane, isoflurane, sevoflurane and desflurane.
10.
Methoxyflurane is an extremely obstetric analgesia, in a manner that foreshadowed the patient-controlled analgesia infusion pumps of today.
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