1. The structure is very similar to that of phosphoenolpyruvate mutase . 2. This is finally transformed using methylmalonyl-CoA mutase . 3. Phosphoenolpyruvate mutase is thought to exhibit a dissociative mechanism. 4. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase . 5. Several tests can be done to discover the dysfunction of methylmalonyl-CoA mutase . 6. Vitamin B is one necessary prosthetic group to the enzyme methylmalonyl-coenzyme A mutase . 7. However, in haemophilus influenzae, prephenate dehydrogenase is fused with the enzyme chorismate mutase . 8. Kinetic and structural studies have provided evidence that indicate dPGM and bisphosphoglycerate mutase are paralogous structures. 9. Methylmalonyl-CoA mutase is a member of the isomerase subfamily of adensylcobalamin-dependent enzymes. 10. People with methylmalonyl CoA mutase deficiency exhibit many symptoms similar to other diseases involving inborn errors of metabolism.
