1. S N 2 is a kind of nucleophilic substitution reaction mechanism. 2. Appropriately functionalized aliphatic compounds undergo nucleophilic substitution with sodium azide. 3. Mesylate is considered a leaving group in nucleophilic substitution reactions. 4. In organic chemistry, ether cleavage is an acid catalyzed nucleophilic substitution reaction. 5. The reaction above is a nucleophilic substitution reaction. 6. Another catalytic use of gold tribromide is in the nucleophilic substitution reaction of propargylic alcohols. 7. An example of nucleophilic substitution is the hydrolysis of an alkyl bromide, Br ". 8. Then, followed by intramolecular nucleophilic substitution , the second hydroxyl group attacks the electron deficient carbon. 9. The anion from the corresponding silver salt is then added by nucleophilic substitution to the iodinium ion. 10. Analogous to benzene, nucleophilic substitutions to pyridine can result in the formation of pyridyne intermediates as heteroaryne.
