1. These included acetanilide, phenacetin , and paracetamol ( acetaminophen ). 2. The sales of phenacetin established Bayer as a leading pharmaceutical company. 3. How phenacetin and other analgesics lead to this damage is incompletely understood. 4. It contained 42 % aspirin, 42 % phenacetin , plus caffeine. 5. Paracetamol was then quickly discarded in favor of phenacetin . 6. Bayer chemists soon developed Phenacetin , followed by the sedatives Sulfonal and Trional. 7. Kast was instrumental in introducing phenacetin and the sulphonal group of drugs into medicine. 8. Together with Julius Axelrod, he discovered that acetanilide and phenacetin both metabolize to paracetamol. 9. Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis. 10. Von Mering claimed that, unlike phenacetin , paracetamol had a slight tendency to produce methemoglobinemia.
