Picorna viruses make up a family of the tiniest known viruses.
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Foot and mouth disease, another picorna virus, costs cattlemen millions of dollars a year.
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For reasons that stumped the scientists, the picorna virus refused to replicate inside yeast cells.
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Varieties of picorna viruses also cause polio and a type of foot-and-mouth disease in animals.
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Picorna viruses are unusual, Dasgupta said, in that ribosomes dock directly onto an internal site on the messenger.
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Compared with other viruses, picorna viruses are exceptionally small and have their own peculiar way of reproducing, Dasgupta said.
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It seems yeast has an RNA molecule that gums up the pathway used by picorna viruses for churning out viral copies.
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After a picorna virus commandeers genetic machinery inside a cell nucleus, it sends messenger molecules out into the cytoplasm where proteins are made.
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But Dasgupta and his group did one thing differently than the Columbia researcher when they found that picorna viruses wouldn't grow in baker's yeast.
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He wanted to use baker's yeast, but to his amazement, the viruses he was working with-- known as picorna viruses-- wouldn't grow in baker's yeast.
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