1. The unqualified term'prostacyclin 'usually refers to PGI 2. 2. Treprostinil is a synthetic analog of prostacyclin ( PGI 2 ). 3. PGE2 and prostacyclin inhibit platelet aggregation and dilate blood vessels. 4. Examples of animal hormones subjected to ion trapping include Prostacyclin and Leukotrienes. 5. This highly unstable compound is rapidly transformed into other prostaglandins, prostacyclin and thromboxanes. 6. It is classified as a prostacyclin analog. 7. Synthetic pathways from PGH 2 ( the parent compound ) to prostaglandins, prostacyclin and thromboxanes 8. It does not stimulate as much prostacyclin and NO to induce relaxation on smooth muscle cells. 9. Instead it uses its heme cofactor to catalyze the isomerization of prostaglandin H 2 to prostacyclin . 10. Today's pulmonary hypertension treatment, prostacyclin , is proved to extend many patients'lives.
