1. The eukaryotic replisome complex is responsible for coordinating DNA replication. 2. Replisome assembly at an origin of replication is roughly divided into three phases.3. The replisome is responsible for copying the entire genomic DNA in each proliferative cell. 4. This section discusses how replisome factors solve the structural and chemical challenges of DNA replication. 5. The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. 6. The CMG complex interacts with the replisome through the interaction with Ctf4 and And1 proteins. 7. Cdc45 then recruits key components of the replisome ; the replicative DNA polymerase ? and its primase. 8. In terms of structure, the replisome is composed of two replicative RNAse H, and ligase. 9. The replisome is a system in which various factors work together to solve the structural and chemical challenges of DNA replication. 10. Once the initiation complex is formed and the cells pass into the S phase, the complex then becomes a replisome .
