1. Upon autopsy, destruction of dopaminergic neurons in the substantia nigra was discovered. 2. It is predominantly expressed in the neocortex, hippocampus, substantia nigra , thalamus, and cerebellum. 3. The nigrostriatal pathway connects the substantia nigra with the dorsal striatum. 4. AmmTX3 also increases spontaneous pacemaking frequency in substantia nigra pars compacta dopaminergic neurons 5. It also involves the substantia nigra , a part of the midbrain. 6. Another arousal system, the dopaminergic system, releases dopamine produced by the substantia nigra . 7. Bradykinesia is correlated with lateralized dopaminergic depletion in the substantia nigra . 8. The vitamin D receptor is strongly expressed in the substantia nigra . 9. A study done shows that after substantia nigra pars reticulata. 10. Degeneration of the substantia nigra is implicated in the cause of Parkinson s disease.
