1. It can be associated with Focal segmental glomerulosclerosis and Charcot-Marie Tooth Disease . 2. By adulthood, Charcot-Marie-Tooth disease can cause painful foot deformities such as pes cavus. 3. There are many factors to why tooth disease and decay occur. 4. These not-so-nice problems include jaw pain, gum and tooth disease and severe overbites. 5. Charcot was among the first to describe Charcot Marie Tooth disease ( CMT ). 6. Like his father, Bailey suffered from Charcot-Marie-Tooth disease for most of his adult life. 7. About 150, 000 Americans have Charcot-Marie-Tooth disease , doctors said. 8. Mutations of the gene are implicated in Charcot-Marie-Tooth disease . 9. For example, kinesin deficiencies have been identified as cause for Charcot-Marie-Tooth disease and some kidney diseases. 10. Mutations in the PDK3 gene are a rare cause of X-linked Charcot-Marie-Tooth disease ( CMTX6 ).