1. Verapamil is also used intra-arterially to treat cerebral vasospasm . 2. Along with physical resistance, vasospasm is a main cause of ischemia. 3. Angina commonly arises from vasospasm of the coronary arteries. 4. A vasospasm is most likely to cause brain damage but can sometimes be deadly. 5. Vasospasm is the major cause of prinzmetal angina.6. This condition can cause complications such as vasospasm , angina pectoris, arrhythmia, ventricular tachycardia. 7. While corticosteroids with mineralocorticoid activity may help prevent vasospasm their use does not appear to change outcomes. 8. Thrombin, a potent vasoconstrictor and mitogen, is implicated as a major factor in vasospasm following subarachnoid hemorrhage. 9. There are multiple mechanisms causing the increased smooth muscle contraction involved in coronary vasospasm , including increased Rho-kinase activity. 10. In 1983, the Russian neurosurgeon Zubkov and colleagues reported the first use of transluminal balloon angioplasty for vasospasm after aneurysmal SAH.