While most of these early studies focused on IgM and IgG, other immunoglobulin isotypes were identified in the 1960s : Thomas Tomasi discovered secretory antibody ( IgA ); David S . Rowe and John L . Fahey discovered IgD; and Kimishige Ishizaka and Teruko Ishizaka discovered IgE and showed it was a class of antibodies involved in allergic reactions.
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