cobalamin sentence in Hindi
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- Cyanocobalamin is usually converted to hydroxocobalamin in the serum, whereas hydroxocobalamin is converted to either methylcobalamin or 5-deoxyadenosyl cobalamin.
- This property allows the convenient preparation of cobalamin analogs with different substituents, via nucleophilic attack on alkyl halides and vinyl halides.
- The protein cubilin binds to intrinsic factor-cobalamin complex and is expressed in the distal small intestine and proximal renal tubule.
- Related areas of interest include the reactivity of metal-carbon bonds, e . g . in cobalamins and the pentacyanocobaltate derivatives.
- The mature enzyme is a homodimer with the N-terminal CoA binding domain and the C-terminal cobalamin-binding domain.
- Thus, acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also be accompanied by an increase in circulating cobalamin.
- The aerobic cobalt chelatase ( aerobic cobalamin biosynthesis pathway ) consists of three subunits, CobT, CobN ( ) and CobS ( ).
- A 2003 study found no significant difference in absorption for serum levels from oral versus sublingual delivery of 0.5 mg of cobalamin.
- In addition, vegetarians, are at risk for consuming a diet low in cobalamin as they voluntarily abstain from animal sources of B 12.
- CODH and ACS often occur together in a tetrameric complex, the CO being transported via a tunnel and the methyl group being provided by methyl cobalamin.
- Her research focuses on the role of organic cofactors as partners of enzymes catalyzing difficult biochemical reactions, especially folic acid and cobalamin ( vitamin B12 ).
- These may be supplemented, although since cyanocobalamin contains the toxic chemical cyanide, dogs that have serious cobalamin issues should instead be treated with hydroxocobalamin or methylcobalamin.
- The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis.
- Additionally, organic acid analysis or quantitative determination of methylmalonic acid should help to exclude cobalamin ( vitamin B12 ) defects and vitamin B12 deficiency giving a differential diagnosis.
- An abnormal result is caused by less of the labeled cobalamin to appear in the urine because it will remain in the intestine and be passed into the feces.
- The gene cluster controlling the biosynthesis of reuterin and cobalamin in the " L . reuteri " genome is a genomic island acquired from an anomalous source.
- Cobalamins are characterized by a porphyrin-like corrin nucleus that contains a single cobalt atom bound to a benzimidazolyl nucleotide and a variable residue ( R ) group.
- Patients of the " cblE " complementation group of disorders of folate / cobalamin metabolism which results in homocystinuria are defective in reductive activation of methionine synthase.
- One cause of elevated plasma B 12 ( cobalamin ) is general liver disease, since hepatic cytolysis releases B 12, and the affected liver shows decreased cobalamin clearance.
- One cause of elevated plasma B 12 ( cobalamin ) is general liver disease, since hepatic cytolysis releases B 12, and the affected liver shows decreased cobalamin clearance.
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