degranulation sentence in Hindi
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- C1P also has known roles in vesicular trafficking, cell survival, phagocytosis ( " cell eating " ) and macrophage degranulation.
- It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane.
- Once activated, eosinophils can begin the process of degranulation, releasing their toxic proteins in the fight against the foreign parasite.
- This CGRP then binds to and activates CGRP receptors located around meningeal vessels, causing vasodilation, mast cell degranulation, and plasma extravasation.
- Finally, NADA can prevent the degranulation and release of TNF from RBL-2H3 mast cells treated with an IgE-antigen complex.
- Fc binds to various cell opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes ).
- The syndrome is diagnosed based upon four sets of criteria involving treatment response, symptoms, a differential diagnosis, and biomarkers of mast cell degranulation.
- Anaphylatoxins are able to trigger degranulation ( release of substances ) of endothelial cells, mast cells or phagocytes, which produce a local inflammatory response.
- The work showed that chemokines not only contribute to leukocyte recruitment, but can cooperate with other mast cell activation signals to trigger mast cell degranulation.
- The toxins are produced by peptides that have multiple actions, such as pain oedema formation, hemolysis, chemotaxis of PMLs and most cell degranulation.
- Complement activation causes a cascade of events leading to : destruction of endothelial cells, platelet degranulation, inflammation, coagulation, fibrin deposition, and hemorrhage.
- At least one clinical study suggested nifedipine, one of the dihydropyridines, may reduce mast cell degranulation in patients who exhibit " urticaria pigmentosa ".
- Eosinophilic cutaneous conditions encompass a wide variety of diseases that are characterized histologically by the presence of eosinophils in the inflammatory infiltrate, or evidence of eosinophil degranulation.
- The degranulation of basophils can be investigated " in vitro " by using flow cytometry and the so-called basophil-activation-test ( BAT ).
- "In vitro " studies have found that ANCAs can activate neutrophils, increase their adherence to endothelium, and induce their degranulation that can damage endothelial cells.
- At least one clinical study suggested that nifedipine, a calcium channel blocker used to treat high blood pressure, may reduce mast cell degranulation in patients with urticaria pigmentosa.
- Nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes.
- Cromoglicate-based drugs ( sodium cromoglicate, nedocromil ) block a calcium channel essential for mast cell degranulation, stabilizing the cell and preventing release of histamine and related mediators.
- Injectable codeine is available for subcutaneous or intramuscular injection only; intravenous injection is contraindicated as this can result in non-immune mast-cell degranulation and resulting anaphylactoid reaction.
- The P2X 7 receptor also serves as a pattern recognition receptor for extracellular ATP-mediated apoptotic cell death, regulation of receptor trafficking, mast cell degranulation, and inflammation.
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