heterochromatin sentence in Hindi
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- Evolutionary dynamics of segmental duplications from human Y-chromosomal euchromatin / heterochromatin transition regions.
- When genes are placed near a region of constitutive heterochromatin, their transcription is usually silenced.
- The quantity and distribution of heterochromatin among both X chromosomes and autosomes is different as well.
- It is a megastructure containing several siRNA which use the RNAi pathway to regulate heterochromatin formation.
- The mechanism by which the RITS complex induces heterochromatin formation and organization is not well understood.
- The heterochromatin can spread stochastically and switch off the color gene resulting in the white eye sectors.
- It specifically stains constitutive heterochromatin, which are regions of the chromosome at or near the centromere.
- Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.
- This suggests that facultative heterochromatin interacts with the polycomb repression complex in order to limit lytic reactivation.
- Heterochromatin protein 1 ( HP1 ) binds both chromatin and the LBR . ONM, outer nuclear membrane.
- Some cancers are associated with anomalies in constitutive heterochromatin and the proteins involved in its formation and maintenance.
- H4K20me3 is observed to be concentrated in heterochromatin and reductions in this trimethylation are observed in cancer progression.
- This is in agreement with findings that show that there is an increase in inactive heterochromatin during differentiation.
- PRC2 acts to create heterochromatin in these regions through similar mechanisms to the mechanism used to repress genes.
- However, on a larger scale, chromosomes are heterogeneous in the context of euchromatin and heterochromatin composition.
- These two complexes localize in a siRNA-dependent manner on chromosomes, at the site of heterochromatin assembly.
- CAF-1 is required for the spatial organization and epigenetic marking of heterochromatin domains in pluripotent embryonic cells.
- There are also three additional euchromatin / heterochromatin transition regions for a total of four on the Y chromosome.
- The rest of the genes lay on the periphery of the sub-nuclear organelle in silenced heterochromatin state.
- This level of chromatin structure is thought to be the form of heterochromatin, which contains mostly transcriptionally silent genes.
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