lagging strand sentence in Hindi
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- However, at the lagging strand, DNA polymerase ? needs to be continually loaded at the start of each Okazaki fragment.
- Since replication occurs in opposite directions at opposite ends of parent chromosomes, each strand is a lagging strand at one end.
- In these plots, a positive deviation from C corresponds to lagging strand and negative deviation from C corresponds to leading strand.
- During normal DNA replication, the polymerase on the lagging strand is required to unclamp and re-clamp the replication region continuously.
- Consider the following : the helicase continuously unwinds the parental duplex, but the lagging strand must be polymerised in the opposite direction.
- This 3'addition provides a template for extension of the 5'end of the daughter strand by lagging strand DNA synthesis.
- DNA-binding proteins that rapidly reassociate post-replication prevent Pol? from repairing errors produced by Pol? in the mature lagging strand.
- There is a richness of guanine over cytosine and thymine over adenine in the leading strand and vice versa for the lagging strand.
- Originally, this asymmetric nucleotide composition was explained as a different mechanism used in DNA replication between the leading strand and lagging strand.
- It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes.
- Furthermore, the time used for replication between the two strands varies and may lead to asymmetric mutational pressure between leading and lagging strand.
- The second school of thought describes the mechanism of GC and AT skew as resulting from differential selective pressure between the leading and lagging strands.
- This happens at all the sites of the lagging strand, but it does not happen at the end where the last RNA primer is attached.
- During DNA replication of circular bacterial genomes, multiple proteins are involved in synthesizing the leading strand, and the Okazaki fragments on the lagging strand.
- On the lagging strand " template ", a primase " reads " the template DNA and initiates synthesis of a short complementary RNA primer.
- Priming enzymes, ( which are DNA-dependent RNA polymerases ), solve this problem by creating an RNA primer on the leading and lagging strands.
- Then, DNA ligase I binds to the PCNA, which is clamped to the nicks of the lagging strand, and catalyzes the formation of phosphodiester bonds.
- The preferred DNA substrate mimics an arrested DNA replication fork with unreplicated lagging strand, structurally identical to a product of recombinational repair of a stalled replication fork.
- There are two problems after leading and lagging strand synthesis : RNA remains in the duplex and there are nicks between each Okazaki fragment in the lagging duplex.
- Due to the fact that an RNA primer is required for initiation of DNA synthesis, the lagging strand is at a disadvantage in replicating the entire chromosome.
lagging strand sentences in Hindi. What are the example sentences for lagging strand? lagging strand English meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.