minichromosome sentence in Hindi
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- The six minichromosome maintenance proteins and Cdc45 are essential during initiation and elongation for the movement of replication forks and for unwinding of the DNA . GINS are essential for the interaction of Mcm and Cdc45 at the origins of replication during initiation and then at DNA replication forks as the replisome progresses.
- ORC, Cdc6, and Cdt1 are all required to load the six protein minichromosome maintenance ( Mcm 2-7 ) complex onto the DNA . The ORC is a six-subunit, Orc1p-6, protein complex that selects the replicative origin sites on DNA for initiation of replication and ORC binding to chromatin is regulated through the cell cycle.
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