phosphocreatine sentence in Hindi
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- If a large group of muscles is still actively drawing fuels from blood after the most recent continuous exercise, in order to replenish the ATP and the phosphocreatine reserve, it may become sour without any additional exercise by the time the carbohydrate meal is finished.
- The functions of these isoenzymes are to convert creatine, using ATP, into phosphocreatine expelling ADP . Mini columns were filled with DEAE-Sephadex A-50 and further eluted with tris-buffer sodium chloride at various concentrations ( each concentration was chosen advantageously to manipulate elution ).
- There is a mitochondrial creatine kinase ( miCK ) present between the inner & outer mitochondrial membranes, which phosphorylates creatine to phosphocreatine at the cost of an ATP molecule ( ATP-- > ADP ), which is exported out the mitochondrion through the pore protein'P'( pages 147-148 ).
- But, an even bigger doubt is how is the reaction creatine-- > phosphocreatine ( requiring 43.1 kJ / mol )-- carried out between the two mitochondrial membranes thermodynamically feasible if ATP-- > ADP releases only 30.5 kJ / mol ( page 126; table 12-1 )?
- My guess, is that it must be faster to transport phosphocreatine out of the mitochondrion than ATP, but I do not know for sure ( as such a thing is not WRITTEN in the text ); then, once in the cytosol, the phosphocreatine must be getting converted back to creatine, phosphorylating ADP to ATP in the process.
- My guess, is that it must be faster to transport phosphocreatine out of the mitochondrion than ATP, but I do not know for sure ( as such a thing is not WRITTEN in the text ); then, once in the cytosol, the phosphocreatine must be getting converted back to creatine, phosphorylating ADP to ATP in the process.
- Once the cell has received a non-trivial load, and has expended the phosphocreatine reserve, a small quantity of ATP will become discharged down to AMP . AMP will instantly up-regulate myophosphorylase, which will start liberating glucose from glycogen and make it available to the glycolytic pathway, producing pyruvate and recharging AMP back to ATP . Due to the greater availability of pyruvate as a substrate, and pyruvate also contributing a citric cycle intermediate, ?-ketoglutarate, while consuming glutamate, the citric acid cycle will also speed up.
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