proximal convoluted tubule sentence in Hindi
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- Concurrent use of diuretics that inhibit the uptake of sodium by the distal tubule ( e . g . thiazides ) is hazardous and should be avoided because this can cause increased resorption of lithium in the proximal convoluted tubule, leading to elevated, potentially toxic levels.
- Under normal conditions in the proximal convoluted tubule of the kidney, most of the carbonic acid ( H 2 CO 3 ) produced intracellularly by the action of carbonic anhydrase quickly dissociates in the cell to bicarbonate ( ) and an ion ( a proton ), as previously mentioned.
- As a result, the filtrate leaving the Bowman's capsule is very similar to blood plasma ( filtrate or glomerular filtrate is composed of blood plasma minus plasma protein i . e . it contains all the components of blood plasma except the proteins ) in composition as it passes into the proximal convoluted tubule.
- The device s design requirements would require the filtration fraction in the glomerulus to vary between 15 %-20 %, or the filtration reabsorption in the proximal convoluted tubule to vary between 65 %-70 %, and finally the urea concentration in urine ( collected at one of the two outlets of the device ) to vary between 200-400mM.
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