therapeutic dose sentence in Hindi
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- Following a declination or total extinction in response to a previously therapeutic dose of an antidepressant, the issue is clinically addressed as stemming from tolerance development.
- On pseudoephedrine, the only over-the-counter decongestant, the American Academy of Family Physicians has recently reported that the range between a therapeutic dose and toxic dose is narrow.
- Trace amounts of theophylline are also found in brewed tea, although brewed tea provides only about 1 mg / L, which is significantly less than a therapeutic dose.
- The generally accepted half-life for a therapeutic dose was not found appropriate in intoxicated patients and would underestimate the time required to reach a safe concentration of the drug.
- In clinical human trials with increasing dosages, vanoxerine has shown to have a highly favourable therapeutic index, showing no side effects at concentrations much higher than the therapeutic dose.
- In early 1941, Hertz administered cyclotron produced a I-130-I-131 mixture as a therapeutic dose to the first human patient at MGH, to a patient with Graves hyperthyroidism, or Graves'disease.
- Regardless of the initial method of preparation, multiple donations may be combined into one container using a sterile connection device to manufacture a single product with the desired therapeutic dose.
- The 25 �g of atropine present in each 2?mg Lomotil tablet is 1 / 40 of the standard therapeutic dose of atropine via the oral route for normal anticholinergic uses.
- The link was strengthened by experiments in the 1970s which suggested that the binding affinity of antipsychotic drugs for D 2 dopamine receptors seemed to be inversely proportional to their therapeutic dose.
- But some limits that have been mentioned by industry include analytical detection levels such as 10 PPM, biological activity levels such as 1 / 1000 of the normal therapeutic dose and organoleptic levels.
- In the human testing phase, there is often a group of subjects, one group is given a placebo, and the other is administered a carefully measured therapeutic dose of the drug in question.
- Withdrawal effects could occur after treatment, lasting only 2 weeks at therapeutic dose levels; however, withdrawal effects tend to occur with habitual use beyond 2 weeks and are more likely the higher the dose.
- This means that even at a therapeutic dose ( 5 �g / kg ), some epibatidine might bind to the muscarinic acetylcholine receptors and cause adverse effects, such as hypertension, bradycardia and muscular paresis.
- Many drivers have blood levels far exceeding the therapeutic dose range and often in combination with other alcohol, illegal, or prescription drugs of abuse, suggesting a high degree of abuse potential for benzodiazepines, zolpidem, and zopiclone.
- In canines, the effective therapeutic dose was between 76 ng / ml and 99 ng / ml, however the drug reached plasma concentrations of 550 ng / ml without harmful side effects, presenting a desirable therapeutic index.
- Erickson, who said baclofen overdose victims routinely stay on respirators for 24 hours, explained that the body can usually rid itself of a therapeutic dose _ 10 to 20 milligrams four times a day _ within 72 hours.
- Two iontophoretic patches have recently been approved for vaso-active therapeutic use by the FDA-Zecuity ( 2013 )-containing the migraine drug sumatriptan-and Ionsys ( 2015 ), indicated for moderate-to-severe acute post-operative pain, delivering a therapeutic dose of the powerful opioid, fentanyl, on-demand.
- Vitamin A, or retinol, is the sole vitamin which is embryotoxic even in a therapeutic dose, for example in multivitamins, because its metabolite, the retinoic acid, plays an important role as a signal molecule in the development of several tisues and organs.
- Merck had already synthesized and patented carbidopa, another dopa decarboxylase inhibitor in 1962, and in 1971 Lotti showed that the use of the L-form of carbidopa, further reduced the therapeutic dose of L-DOPA . The combination of L-carbidopa and L-DOPA was marketed under the brand name of Sinemet.
- In a double-center, dose escalation Phase I / IIa clinical trial of BC-819 as a treatment for superficial bladder cancer, no severe adverse events related to the plasmid were detected, and tumor responses were observed in more than 70 % of patients, including those with a still not-optimized therapeutic dose and regimen.
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