virilization sentence in Hindi
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- A genital skin fibroblast study and a human chorionic gonadotropin ( hCG ) stimulation test may also provide information helpful in the assessment of virilization capacity.
- Another common disorder is congenital adrenal hyperplasia where the adrenal glands produce excessive sex hormones during development leading to virilization of a 46, XX female.
- Cases of virilization caused by topical exposure to testosterone are rare in the medical literature, said Dr . Y . Miles Yu, the lead author of the study.
- Often present are increased muscle mass, clitoral enlargement may occur in girls, and sometimes a degree of prenatal virilization is recognized that may have gone unnoticed in infancy.
- The most common instance of this is when a child will be assigned and raised as a female despite complete virilization, as with Prader 5 reassigned as a female.
- Case reports of significant virilization of young children after exposure to topical androgen preparations ( both prescription and'supplement'products ) used by their caregivers demonstrates this very real risk.
- With greater degrees of virilization, the major challenge of the procedure is to provide a passage connecting the outer vaginal opening to the cervix which will stay wide enough to allow coitus.
- Theoretically, if enough glucocorticoid could be supplied to the fetus to reduce adrenal testosterone production by the 9th week, virilization could be prevented and the difficult decision about timing of surgery avoided.
- The excess of adipose tissue in obese women creates the paradox of having both excess androgens ( which are responsible for hirsutism and virilization ) and estrogens ( which inhibits FSH via negative feedback ).
- Milder forms resulting from incomplete loss of 3?-HSD type II function do not present with adrenal crisis, but can still produce virilization of genetically female infants and undervirilization of genetically male infants.
- If a normal internal uterus, cervix and upper vagina ( the M�llerian derivatives ) exist, and the outer virilization is modest, surgery involves separating the fused labia and widening the vaginal introitus.
- The "'clitoral index "', defined as the product of the sagittal and transverse dimensions of the glans clitoridis, is sometimes used as a measure of virilization in women.
- AR antagonists may not bind to or block membrane androgen receptors ( mARs ), which are distinct from the classical nuclear AR . However, the mARs do not appear to be involved in virilization.
- Women who are administered oxandrolone may experience virilization, the non-reversible development of masculine features such as voice deepening, hirsutism, menstruation abnormalities, male-pattern hair loss, and clitoral enlargement.
- Instead, androgens will elevate once again above normal levels, and may cause additional virilization, such as acne, hirsutism, and further enlargement of the clitoris, unless treatment with estrogen is given.
- De novo ( i . e . a somatic mutation ); a certain amount of the wild-type androgen receptor will be present in cases of somatic mutation, which can induce virilization at puberty.
- No additional testosterone is given during childhood, to avoid unwanted virilization and bone maturation . ( There is also some evidence that premature administration of testosterone can lead to reduced penis size in the adult .)
- The challenge of preventing severe virilization of girls is twofold : detection of CAH at the beginning of the pregnancy, and delivery of an effective amount of glucocorticoid to the fetus without causing harm to the mother.
- Many of the myths stem from high-dose testosterone treatments for other, unrelated medical conditions, which can cause virilization _ growth of facial hair, loss of scalp hair, deepening of the voice and weight gain.
- Use of the patch resulted in virilization in five men who had never gone through puberty, including a 51-year-old man who developed pubic and facial hair and an enlarged penis for the first time in his life.
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