virilize sentence in Hindi
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- The condition, the most common intersex diagnosis, often causes a baby girl's genitals to be " virilized "-to look something like a boy's.
- Most of the cases in which a child or adult has voluntarily changed sex and rejected rearing have occurred in partially or completely virilized genetic males who were reassigned and raised as females.
- As well, " Anabolic androgenic steroids produce anabolic and virilizing ( also known as androgenic ) effects . "-Gee, who would guess that anabolic androgenic steroids were anabolic and androgenic?
- Sex cord-stromal tumor, including estrogen-producing granulosa cell tumor, the benign thecoma, and virilizing Sertoli-Leydig cell tumor or arrhenoblastoma, accounts for 7 % of ovarian cancers.
- The clinical features of hyperthecosis are similar to those of PCOS . However, women with hyperthecosis often have more markedly elevated testosterone, more hirsutism, and are much more likely to be virilized.
- These women have a 46, XY karyotype ( i . e ., are genetically " male " ) and high levels of androgens but possess a defective AR and for this reason never virilize.
- Classic CAH, the disorder targeted by newborn screening programs, is caused by a deficiency of the enzyme steroid 21-hydroxylase, and comes in two forms-simple virilizing and a salt-wasting form.
- The growth problem is even worse in the simple virilizing forms of CAH which are detected when premature pubic hair appears in childhood, because the bone age is often several years advanced at the age of diagnosis.
- This approach was designed to preserve fertility for both sexes and remains the standard management, but two aspects of this management have been challenged : assignment of completely virilized genetic females and the value and age of corrective surgery.
- The more " virilized " the appearance, the more likely parents will choose surgery, said Kelly R . Leight, executive director of the CARES Foundation, a support and educational group for families affected by congenital adrenal hyperplasia.
- The more virilized phenotypes of AIS have sometimes been described as " undervirilized male syndrome ", " infertile male syndrome ", " undervirilized fertile male syndrome ", etc ., before evidence was reported that these conditions were caused by mutations in the " AR " gene.
- While a boy ( or girl ) with simple virilizing CAH is taller than peers at that point, he will have far fewer years remaining to grow, and may go from being a very tall 7-year-old to a 62-inch 13-year-old who has completed growth.
- As their name suggests, AAS have two different, but overlapping, types of effects : " anabolic ", meaning that they promote anabolism ( cell growth ), and " androgenic " ( or " virilizing " ), meaning that they affect the development and maintenance of masculine characteristics.
- The lack of virilizing effects means that S-40503 may even be suitable for use in women, which would be a substantial advantage over existing drugs as women tend to be more likely to suffer from osteoporosis, and are generally contraindicated from taking anabolic steroids due to the risk of side effects such as masculinisation and hirsutism.
- Because AMH expression is critical to sex differentiation at a specific time during fetal development, it appears to be tightly regulated by SF1, GATA factors, DAX1 and FSH . Mutations in both the AMH gene and the type II AMH receptor have been shown to cause the persistence of M�llerian derivatives in males that are otherwise normally virilized.
- This suggests that, while SARMs are likely to show some virilizing effects when used at high doses ( e . g ., use by bodybuilders ), at lower therapeutic doses they may well be effectively selective for anabolic effects, which will be important if SARMs are to have clinical application in the treatment of osteoporosis in women.
- "' 11?-Hydroxylase deficient congenital adrenal hyperplasia "'( "'11?-OH CAH "') is an uncommon form of congenital adrenal hyperplasia ( CAH ) resulting from a defect in the gene encoding the enzyme steroid 11?-hydroxylase which mediates the final step of cortisol synthesis in the virilize a genetically female fetus or a child of either sex.
- In all its forms, congenital adrenal hyperplasia due to 21-hydroxylase deficiency accounts for about 95 % of diagnosed cases of CAH . Unless another specific enzyme is mentioned, " CAH " in nearly all contexts refers to 21-hydroxylase deficiency . ( The terms " salt-wasting CAH ", and " simple virilizing CAH " usually refer to subtypes of this condition . ) CAH due to deficiencies of enzymes other than 21-hydroxylase present many of the same management challenges as 21-hydroxylase deficiency, but some involve mineralocorticoid excess or sex steroid deficiency.
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