hamartoma sentence in Hindi
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- In one of nature's cruel ironies, the laughter is a symptom of hypothalamic hamartoma, an extremely rare disorder that brings sorrow to the victims and their families.
- Mutations in the " PTEN " gene cause several other disorders that, like Cowden syndrome, are characterized by the development of non-cancerous tumors called hamartomas.
- Moreover, even though hamartomas show a benign histology, it does not eliminate some rare but life-threatening clinical issues such as those found in tuberous sclerosis and neurofibromatosis type I.
- It has been associated with several different conditions such as temporal and frontal lobe lesions, tumors, atrophy, tuberous sclerosis, hemangiomas, and post infectious foci, but mainly hypothalamic hamartomas.
- Cowden syndrome is an autosomal dominant genetic disorder characterised by multiple benign hamartomas ( trichilemmomas and mucocutaneous papillomatous papules ) as well as a predisposition for cancers of multiple organs including the breast and thyroid.
- Nicholas was the 50th patient worldwide on whom Dr . Jeffery Rosenfeld has performed his highly successful surgical technique to treat hypothalamic hamartoma, or " HH " as it is called in family support groups.
- Rosenfeld is the world's foremost expert in the surgical treatment of hypothalamic hamartoma, said Dr . David Pincus, clinical assistant professor in the neurological surgery department of UF's College of Medicine.
- The tumor, known as a hamartoma, was located at the base of the brain, near the hypothalamus _ which controls eating, sleeping and other actions _ and the optic nerve, which controls sight.
- Hamartomas are typically benign; however, people with Cowden syndrome are at increased risk of developing several types of cancer, including cancers of the breast, thyroid, uterus ( endometrial ), and kidney cancers.
- Together, the disorders caused by " PTEN " mutations are called PTEN hamartoma tumor syndromes, or PHTS . Mutations responsible for these syndromes cause the resulting protein to be non-functional or absent.
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