lagging strand sentence in Hindi
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- Further optimization can be achieved by designing oligos that target the lagging strand in DNA replication because targeting the lagging strand results in a higher frequency of recombinants.
- Further optimization can be achieved by designing oligos that target the lagging strand in DNA replication because targeting the lagging strand results in a higher frequency of recombinants.
- High processivity is in part ensured by ring-shaped proteins referred to as'clamps'that help replicative polymerases stay associated with the leading and lagging strands.
- The discontinuous stretches of DNA replication products on the lagging strand are known as Okazaki fragments and are about 100 to 200 bases in length at eukaryotic replication forks.
- In DNA replication, RNA primers must be inserted along the lagging strand so that DNA polymerase is able to synthesize the strand in the 5 to 3 direction.
- The leading strand is continuously extended from the primer by a DNA polymerase with high processivity, while the lagging strand is extended discontinuously from each primer forming Okazaki fragments.
- The " oriC " site in " E . coli " has three primer for the leading strand and to add RNA primers on the lagging strand.
- This means that, while polymerisation of the leading strand proceeds, polymerisation of the lagging strand only occurs after enough of the lagging strand has been unwound by the helicase.
- This means that, while polymerisation of the leading strand proceeds, polymerisation of the lagging strand only occurs after enough of the lagging strand has been unwound by the helicase.
- The single stranded ( ss ) DNA synthesized during lagging strand synthesis can be targeted by ss-DNA damaging agents as well as is a selective target for APOBEC mutations.
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