physostigmine sentence in Hindi
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- Later studies showed that physostigmine binds to the enzyme that normally soaks up free acetylcholine, preventingbthe enzyme from doing its job and thereby prolonging the action of acetylcholine.
- The metabolite thus formed from physostigmine and some other alkaloids ( e . g . cymserine ) is eseroline, which research has suggested may be neurotoxic to humans.
- Physostigmine, a choline-esterase inhibitor, elevates endogenous levels of acetylcholine by stimulation of the RVLM . Orexinergic neurons from the lateral hypothalamus output in the RVLM.
- The difference is, sarin binds permanently, sending the muscles into spasm and causing long-term nerve damage, while physostigmine releases the enzyme after a short interval.
- Today, physostigmine is most commonly used for its medicinal value but before its discovery by Sir Robert Christison in 1846, it was much more prevalent as a poison.
- In this preparation, MLA-treated muscle responded normally to " direct " electrical stimulation, but the inhibition of contractions was only partially antagonized by physostigmine.
- In addition, some carbamates are used in human pharmacotherapy, for example, the acetylcholinesterase inhibitors neostigmine and rivastigmine, whose chemical structure is based on the natural alkaloid physostigmine.
- Physostigmine's poor tolerability led to it being abandoned in favor of later acetylcholinesterase inhibitors, three of which are currently in use : donepezil, galantamine, and rivastigmine.
- She had noted that the symptoms and signs of myasthenia were similar to those found in curare poisoning, and physostigmine was used as an antidote to curare poisoning at that time.
- A further ( still controversial ) proposal was his creation of a system of Lethal injection ( through the discovery of Physostigmine in 1846 ) for human execution, in place of hanging.
physostigmine sentences in Hindi. What are the example sentences for physostigmine? physostigmine English meaning, translation, pronunciation, synonyms and example sentences are provided by Hindlish.com.