therapeutic dose sentence in Hindi
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- Atropine is purposely added at 25 micrograms per tablet, or 1 / 24 to 1 / 40 of the usual therapeutic dose for atropine to minimize the potential of misuse by swallowing large numbers of tablets or preparing them for injection since difenoxin is chemically related to the pethidine-piritramide subgroup of the opioid family, and could theoretically be misused.
- The Thorough QT / QTc study was designed to assess the effect on the QT / QTc interval, both of the therapeutic dose ( 20 mg ) and 100 mg of bilastine, but also the coadministration of the therapeutic dose with usual doses of ketoconazol ( 400 mg / day ), a metabolism inhibitor and a P-gP dependent transport system.
- The Thorough QT / QTc study was designed to assess the effect on the QT / QTc interval, both of the therapeutic dose ( 20 mg ) and 100 mg of bilastine, but also the coadministration of the therapeutic dose with usual doses of ketoconazol ( 400 mg / day ), a metabolism inhibitor and a P-gP dependent transport system.
- In over-the-counter formulations, DXM is often combined with acetaminophen ( paracetamol, APAP ) to relieve pain and to prevent recreational use; however, to achieve DXM's dissociative effects, the maximum daily therapeutic dose of 4000 mg of APAP is often exceeded, potentially causing acute or chronic liver failure, making abuse and subsequent tolerance of products which contain both DXM and APAP potentially fatal.
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