thiol group sentence in Hindi
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- It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons.
- Cysteine has traditionally been considered to be a hydrophilic amino acid, based largely on the chemical parallel between its thiol group and the hydroxyl groups in the side-chains of other polar amino acids.
- This acetate, bound to the active thiol group of coenzyme A, enters the " citric acid cycle " ( TCA cycle ) where it is fully cells to obtain energy from fat.
- The His343 residue at the active site of CRAT acts as a base that is able to deprotonate the CoA thiol group or the Carnitine 3-hydroxyl group depending on the direction of the reaction.
- Another suggestion is that methylation might be a detoxification if " As [ III ] intermediates are not permitted to accumulate " because the pentavalent organoarsenics have a lower affinity to thiol groups than inorganic pentavalent arsenics.
- Finally, a molecule of inorganic phosphate attacks the thioester and forms a tetrahedral intermediate, which then collapses to release 1, 3-bisphosphoglycerate, and the thiol group of the enzyme's cysteine residue.
- The thiol groups are also of great importance in substrate binding of enzymes, in metal-sulfur clusters in proteins ( e . g . ferredoxins ) and in regulatory proteins ( e . g . thioredoxins ).
- Here is the possible mechanism of action [ 2 ] : Firstly, the thiol group of FabF Cys163 is activated through the dipole moment of helix N-alpha-3 which lowers the pKa of this functional group.
- Since disulfide bond formation is an oxidative process, the major pathway of its catalysis has evolved to utilise oxidoreductases, which become reduced during the thiol-disulfide exchange reactions that oxidise the cysteine thiol groups of nascent polypeptides.
- "' 8-Mercaptoquinoline "'is the organosulfur compound with the formula C 9 H 7 NSH . It is a derivative of the heterocycle quinoline, substituted in the 8-position with a thiol group.
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