HES is a diagnosis of exclusion, after clonal eosinophilia ( such as leukemia ) and reactive eosinophilia ( in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer ) have been ruled out.
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Viswanathan was credited with pioneering research in bronchopulmonary diseases and was reported to be the first researcher to propose tropical eosinophilia as a distinct clinical entity in 1936 . " Diseases of the Chest ", " Medical Problems of Old Age " and more than 230 medical articles in peer reviewed journals, " Epidemiology ", " Infectious hepatitis in Delhi ( 1955-56 ) : a critical study-epidemiology " and " A review of the literature on the epidemiology of infectious hepatitis " being some of the notable ones; his articles and books have been cited in several medical journals and text books, too.
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