1. In neuroacanthocytosis, acanthocytes are caused by protein but not lipid membrane abnormalities 2. This results in abnormally shaped red cells called acanthocytes . 3. Acanthocytes are nearly always present in these conditions and they share common clinical features.4. This causes abnormalities of membrane of RBC causing remodeling in spleen and formation of acanthocytes . 5. Acanthocytes are seen on blood smear.6. These thorny cells are called acanthocytes . 7. Acanthocytes have coarse, irregularly spaced, variably sized crenations, resembling many-pointed stars.8. None form acanthocytes on their mycelia. 9. Echinocytes are frequently confused with acanthocytes , but the mechanism of cell membrane alteration is different. 10. The fungus produces acanthocytes , which are spiny cells produced on short branches on the mycelium.