Acrodermatitis enteropathica is a rare autosomal recessive disorder, which is a consequence of a defective intestinal absorption.
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"Acrodermatitis chronica atrophicans " ( ACA ) is a chronic skin disorder observed primarily in Europe among the elderly.
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Zinc supplement is an effective treatment for acrodermatitis enteropathica, a genetic disorder affecting zinc absorption that was previously fatal to affected infants.
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This disease also is related to deficiency of zinc due to congenital causes . Other names for " acrodermatitis enteropathica " include:
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The treatment of acrodermatitis enteropathica requires zinc supplementation with 1 3 mg D kg D day of zinc, with patients requiring a higher dosage of zinc during adolescence, pregnancy.
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Research in Europe had found that erythema migrans and acrodermatitis chronica atrophicans, another rash caused by ticks in Europe, responded to penicillin, suggesting that the cause was bacterial, not viral.
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Zinc deficiency is usually due to insufficient dietary intake, but can be associated with malabsorption, acrodermatitis enteropathica, chronic liver disease, chronic renal disease, sickle cell disease, diabetes, malignancy, and other chronic illnesses.
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The first study dates to 1883 in Breslau, Germany ( now WrocBaw, Poland ), where physician Alfred Buchwald described a man who had suffered for 16 years with a degenerative skin disorder now known as acrodermatitis chronica atrophicans.
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Hypozincemia is usually a nutritional deficiency, but can also be associated with malabsorption, diarrhea, acrodermatitis enteropathica, chronic liver disease, chronic renal disease, sickle-cell disease, diabetes, malignancy, pyroluria, and other chronic illnesses.
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Symptoms outside of the liver are present in 1 10 % of HBV-infected people and include serum-sickness like syndrome, acute necrotizing vasculitis ( polyarteritis nodosa ), membranous glomerulonephritis, and papular acrodermatitis of childhood ( Gianotti Crosti syndrome ).
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