1. The importance of acrosin in the acrosome reaction has been contested. 2. The second process in sperm activation is the acrosome reaction. 3. After reaching the zona pellucida the actual acrosome reaction begins. 4. Acrosin is the major proteinase present in the acrosome of mature spermatozoa. 5. It is stored in the acrosome in its precursor form, proacrosin. 6. Upon stimulus, the acrosome releases its contents onto the zona pellucida. 7. This test evaluates the acrosome reaction of human spermatozoa. 8. Other cells will spontaneously shed their acrosome during the process of apoptosis / necrosis. 9. The sperm of " C . elegans " is ameboid, lacking flagella and acrosomes . 10. Sperm that are unable to properly go through the acrosome reaction will not be able to fertilize an egg.