1. Polyphosphoric acids are used in organic synthesis for cyclizations and acylations . 2. In the acylation reaction, AlCl 3 complexes with the product. 3. The third reaction involved intermediate XVII undergoing acylation using acetyl chloride. 4. For the acylation reaction a stoichiometric amount of aluminum trichloride is required. 5. Therefore, more insulin will bind to receptors when acylation decreases, causing hypoglycemia. 6. Acylation can be used to prevent rearrangement reactions that would normally occur in alkylation.7. Pseudoephedrine amides are typically prepared by acylation with an acid chloride or acid anhydride. 8. The ratio between alkylation and acylation depends on the substrate and the reaction conditions. 9. The compound is prepared by acylation of 2-bromopyridine via the Grignard reagent. 10. In the Friedel Crafts acylation , acid halides act as electrophiles for electrophilic aromatic substitution.
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