1. The cold agglutinin detected is of anti-i specificity. 2. This is the case in both cold agglutinin disease and cold paroxysmal hematuria. 3. Individuals with cold agglutinin disease present with signs and symptoms of hemolytic anemia. 4. It was recognized that the serum of the reported woman agglutinin when described. 5. There are also reports of eculizumab being used to treat cold agglutinin disease. 6. Cold agglutinins , or cold autoantibodies, occur naturally in nearly all individuals. 7. Its seeds contain high activity of soybean lectins ( soybean agglutinin or SBA ). 8. In individuals that have cold agglutinin disease, the lifespan of erythrocytes is shortened. 9. Those with secondary agglutinin disease may also present with an underlying disease, often autoimmune. 10. In chronic cold agglutinin disease, the patient is more symptomatic during the colder months.
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