1. In translation, complementary tRNA anticodon sequences to mRNA codons. 2. The ribosome must discriminate between correct and incorrect codon-anticodon pairs. 3. An interesting example of A-minor is its role in anticodon recognition. 4. Cytoplasmic tRNA genes can be grouped into 49 families according to their anticodon features. 5. The reason is that the ribosome only sees the anticodon of the tRNA during translation. 6. The tRNA anticodon domain associates with the mRNA codon domain in the ribosomal A site. 7. This modification is necessary to stabilize the anticodon -codon pairing and correctly translate the mRNA. 8. It is complementary to the anticodon of the tRNA that is a substrate of the tRNA synthetase under regulation. 9. Thus, the ribosome will not be able to discriminate between tRNAs with the same anticodon but linked to different amino acids. 10. Aminoacyl tRNA synthetases ( enzymes ) catalyze the bonding between specific tRNAs and the amino acids that their anticodon sequences call for.
Mobile