1. Bumetanide is therefore currently under evaluation as a prospective antiepileptic drug. 2. Antihaemorhagic and antiepileptic usages are recorded in local ethnomedicine of Brazil. 3. Antiepileptics can be used for symptomatic relief of peripheral nerve hyperexcitability.4. Several antiepileptic drugs have multiple or uncertain mechanisms of action. 5. For example, PDE compromised the antiepileptic activity of adenosine. 6. In most cases VNS does not replace antiepileptic medication. 7. Antiepileptic medication is administered to help prevent seizures.8. Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs. 9. Other antiepileptic drugs may therefore be preferred for the long-term management of epilepsy. 10. First line therapy for epilepsy involves treatment with anticonvulsive drugs, also called antiepileptic drugs.