1. Damiana's anxiolytic properties might be due to apigenin . 2. Apigenin is a antagonist of all three opioid receptors.3. Various species contain apigenin , luteolin, quercetin, other flavonoids and ecdysteroids. 4. CYP93G1 of the CYP P450 superfamily in rice then desaturates naringenin into apigenin . 5. Apigenin dimers can reverse the highest level of drug resistance found in cancer stem cells.6. Apigenin readily crosses the blood-brain barrier and has not demonstrated toxicity at high doses.7. The aglycone of apiin is apigenin . 8. Plants contain aglycones : apigenin , chrysoeriol, isorhamnetin, kaempferol, luteolin, quercetin . and rutin 9. Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property.10. Apigenin and luteolin, compounds found in the plant, may help fight influenza virus ( H3N2 ).