1. It is characterized by lowered activity of arginase in hepatic cells. 2. Arginase catalyzes the hydrolysis of arginine to ornithine and urea.3. Arginase transcript variants encoding different isoforms have been found for this gene.4. Specifically, arginase converts L-arginine into L-ornithine and urea. 5. Mammalian arginase is active as a trimer, but some bacterial arginases are hexameric. 6. Arginase 's active site is extraordinarily specific.7. Arginase deficiency, unlike other urea cycle disorders, does not entirely prevent ureagenesis.8. There are several arginase isozymes that differ in catalytic, molecular and immunological properties. 9. Ammonia and arginine are thought to cause neurological problems and other symptoms of arginase deficiency. 10. Arginase is about the enzyme reaction and has links back to both ARG1 and ARG2.
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