1. Capacitation involves a specific pattern of hyperactivated wiggling.2. In mammals, spermatozoa mature functionally through a process which is known as capacitation . 3. By this point, capacitation has finished. 4. CRISP1 binds to surface of the sperm leading to a quiescent state of storage prior to capacitation . 5. Hyperactivation coincides with the onset of capacitation and is the result of the increased Ca 2 + levels. 6. After this capacitation , the sperm must undergo the final maturation step, activation, involving the acrosome reaction. 7. It may function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction. 8. The final phase of sperm development, where its ability to fertilize is " switched on, " is called capacitation . 9. Non-mammalian spermatozoa do not require this capacitation step and are ready to fertilize an oocyte immediately after release from the male. 10. In mice, group III sPLA2 are involved in sperm maturation, and group X are thought to be involved in sperm capacitation .
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