1. Ceruloplasmin is the major copper-carrying protein in the blood.2. The molecular weight of human ceruloplasmin is reported to be 151kDa. 3. The liver also releases copper into the bloodstream that is not bound to ceruloplasmin . 4. Ceruloplasmin carries more than 95 % of the total copper in healthy human plasma.5. Shows the ceruloplasmin level ranges for Wilson's disease patients and healthy adults. 6. The A domains are homologous to the A domains of the copper-binding protein ceruloplasmin . 7. Hephaestin presents homology with ceruloplasmin , a serum dehydrogenase protein involved in copper detoxification and storage. 8. Ceruloplasmin is an enzyme ( ) synthesized in the liver containing 6 atoms of copper in its structure.9. Fortunately, copper deficiency can be confirmed by very low serum metal and ceruloplasmin concentrations in the blood. 10. Ceruloplasmin is the major copper-carrying protein in the blood, and in addition plays a role in iron metabolism.
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