Following the initial chondrification that occurs during embryogenesis, cartilage growth consists mostly of the maturing of immature cartilage to a more mature state.
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Chondrification ( also known as chondrogenesis ) is the underlying process of cartilage formation from condensed mesenchyme tissue, which differentiates into chondrocytes and begins secreting the molecules that form the extracellular matrix, the cartilage repair tissue.
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When referring to bone, or in this case cartilage, the originally undifferentiated mesenchymal stem cells lose their pluripotency, proliferate and crowd together in a dense aggregate of chondrogenic cells ( cartilage ) at the location of chondrification.
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Chondrification ( also known as chondrogenesis ) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules ( aggrecan and collagen type II ) that form the extracellular matrix.
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