Evidence of the heterodimerization of survivin splice variants with survivin was shown with co-immunoprecipitation experiments after cotransfection with the respective survivin variants with survivin.
2.
In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B ( NFKB )-dependent reporter gene, consistent with a role in the SAPK pathway.
3.
Following the completion of his graduate studies, he trained as post-doctoral fellow on molecular genetics of cotransfection method for marker rescue mapping of mutations and introduction of new sequences into the HSV genome and showed that the ICP4 gene mapped in the repeated sequences of the short component of the viral genome.
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