Elevated levels of macroglobulins ( macroglobulinemia ) may cause manifestations of excess blood viscosity ( as is the case for IgM antibodies in Waldenstr�m macroglobulinemia ) and / or precipitate within blood vessels when temperature drops ( as in cryoglobulinaemia ).
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"' Cryoglobulinemia "'or "'cryoglobulinaemia "'is a medical condition in which the blood contains large amounts of cryoglobulins proteins ( mostly cold agglutinins, which cause agglutination of red blood cells.
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