Further research led to the development of synthesized molecules with different curariform effects, depending on the distance between the quaternary ammonium groups.
2.
Another compound malou�tine that was a " bis "-quaternary steroid was isolated from the plant " Malouetia bequaertiana " and showed curariform activity.
3.
Citing the work of other investigators, Graham noted that Birchall had also produced " alarming curariform effects " in humans with i . v . doses of 32 mg / kg of tetraethylammonium chloride.
4.
In one subject, described as a " healthy woman ", 300 mg of tetraethylammonium bromide, i . v ., produced incapacitating " curariform " ( i . e ., resembling the effects of tubocurarine ) paralysis of the skeletal muscles, as well as marked drowsiness.
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