1. Endogenous sulfur dioxide in low concentrations causes endothelium -dependent vasodilation. 2. Damage to the blood vessel lining or endothelium is particularly important. 3. Runx1 has also been implicated in the activation of haemogenic endothelium . 4. Thus KLF2 has an important role in regulating normal endothelium physiology. 5. Initial damage to the endothelium results in an inflammatory response. 6. Intact endothelium can prevent this smooth muscle proliferation by releasing nitric oxide. 7. The valvular endothelium is a prominent site of lymphocyte-induced damage. 8. The endothelium begins to control muscle tone and arteriolar blood flow tissue. 9. Endothelium of the interior surfaces of the heart chambers is called endocardium.10. If the endothelium is damaged, cholinergic stimulation causes vasoconstriction.
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