PTX3 behaves as an endotoxic shock, sepsis and other inflammatory and infectious conditions, correlating with the severity of the disease.
2.
Ideally, prophylactic treatment should be provided to endotoxic horses, which includes the use of NSAIDs, DMSO, icing of the feet, and frog support.
3.
Clinical signs are similar to those of other diarrheal diseases, including toxemia caused by " Clostridium ", Potomac horse fever, experimental endotoxic shock, and anaphylaxis.
4.
Though IL-1 is useful in combating some diseases, endotoxic bacteria have gained an advantage by forcing the hypothalamus to increase cortisol levels ( forcing the secretion of corticotropin-releasing hormone, thus antagonizing IL-1 ).
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