1. His test detects epigenetic modifications, in particular, DNA methylation. 2. Another model of epigenetic function is the " trans " model. 3. Epigenetic control is often associated with alternative covalent modifications of histones.4. Fluoroquinolone antibiotics induce epigenetic changes in mammalian cells through iron chelation. 5. The significance of epigenetic inheritance to the evolutionary process is uncertain. 6. Many cancers arise from the inappropriate epigenetic effects of misregulated methylation. 7. In some organisms, it is strictly required for epigenetic silencing. 8. DDR genes are often repressed in human cancer by epigenetic mechanisms. 9. There may be a conserved epigenetic mark that drives this preference. 10. The process is guided by small RNAs and epigenetic chromatin marks.
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