1. The liver is often moderately enlarged, with foci of extramedullary hematopoiesis. 2. CD markers can aid in the distinction of extramedullary plasmacytoma from lymphomas. 3. The fetal response to is variable and may include compensatory extramedullary hematopoiesis. 4. Paraproteins are present in 60 % of SPB and less than 25 % of extramedullary plasmacytoma. 5. The criteria for extramedullary plasmacytoma are the same but the tumor is located in soft tissue. 6. Another complication of extramedullary hematopoiesis is poikilocytosis, or the presence of abnormally shaped red blood cells. 7. Tissue biopsies of SPB and extramedullary plasmacytoma are used to assess the phenotype of the plasma cells. 8. The intradural network breaks down into the intramedullary and extramedullary systems which are sets of highly reliable veins. 9. There may be evidence of extramedullary hematopoiesis ( marrow elements can be found in the spleen, liver ). 10. They recognise three distinct entities : SPB, extramedullary plasmacytoma and multiple solitary plasmacytomas ( + /-recurrent ).