1. In arterial vascular tissue, glycocalyx disruption causes inflammation and atherothrombosis. 2. The slime on the outside of a fish is an example of glycocalyx . 3. Light dye damaged the glycocalyx minimally, but that small change increased capillary hematocrit. 4. This takes into account both the glycocalyx and spectrin layers of the erythrocyte membrane. 5. These studies are evidence that the glycocalyx plays a crucial role in cardiovascular system health. 6. In microvasculature, dysfunction of the glycocalyx leads to internal fluid imbalance, and potentially edema. 7. Fluid shear stress is also a potential problem if the glycocalyx is degraded for any reason. 8. The enzymes and proteins listed above serve to reinforce the glycocalyx barrier against vascular and other diseases. 9. Initial dysfunction of the glycocalyx can be caused by hyperglycemia or oxidized LDL which then causes atherothrombosis. 10. Experiments have been performed in order to test precisely how the glycocalyx can be altered or damaged.
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