1. Affects medium and small vessels with vascular and extravascular granulomatosis . 2. An earlier name for the disease was " pathergic granulomatosis ". 3. Examples include giant cell arteritis, microscopic polyangiitis, and granulomatosis with polyangiitis. 4. It is most commonly due to granulomatosis with polyangiitis or Goodpasture's syndrome. 5. It is sometimes considered to be part of a spectrum with granulomatosis with polyangiitis. 6. The disease is still sometimes confused with lethal midline granuloma and lymphomatoid granulomatosis , both malignant lymphomas. 7. Much less common causes for perforated nasal septums include rare granulomatous inflammatory conditions like granulomatosis with polyangiitis. 8. Granulomatosis with polyangiitis usually presents with nasopharyngeal involvement as well, whereas Goodpasture's will not.9. This condition is now called " eosinophilic granulomatosis with polyangiitis " to remove all eponyms from the vasculitides. 10. Even highly unusual conditions, such as the inflammatory disease Wegener's Granulomatosis , have an Internet presence.
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