1. Hirudin ( and related substances ) are synthesised using recombinant techniques.2. Several other direct thrombin inhibitors are derived chemically from hirudin . 3. Hirudin is the most potent natural inhibitor of thrombin.4. Therefore, hirudin prevents or dissolves the formation of clots and complexed thrombin. 5. The active anticoagulant component of leech saliva is a small protein, hirudin . 6. Bleeding may continue for some time, due to the leech's hirudin . 7. Revasc, also known as hirudin , is genetically-engineered from the saliva of leeches. 8. The results are expected to show Hirudin is no more effective than heparin, the current standard. 9. The three studies aimed in part at comparing heparin, which was discovered in 1916, and hirudin . 10. Unlike antithrombin, hirudin binds to and inhibits only the activated thrombin, with a specific activity on fibrinogen.
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