1. A single normal IGF-1 value will reliably exclude GH hypersecretion . 2. The course of action ultimately depends on the cause of the hypersecretion . 3. Hypersecretion is more common than hyposecretion.4. Hypersecretion of mucus can occur in inflammatory respiratory diseases such as respiratory expectorating phlegm from the throat.5. Ectopic production of large amounts of ADH leads to syndrome of inappropriate antidiuretic hormone hypersecretion ( SIADH ). 6. This phenomenon of hypersecretion is called the Arias-Stella phenomenon, after the pathologist Javier Arias-Stella. 7. It does not undergo diurnal variation and will thus be consistently elevated in GH hypersecretion and therefore patients with gigantism. 8. Increases in these facilitate memory, but chronic stress associated with prolonged hypersecretion of cortisol may have the opposite effect. 9. Insulin-like Growth Factor-1 ( IGF-1 ) is an excellent test for evaluation of GH hypersecretion . 10. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease ( COPD ).
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